Effects of Varidase buccal tablets on the sputum

Nagaoka, S.; Yamanaka, E.; Nakazawa, Y.; Katano, F.

Clinical Therapeutics 3(2): 137-142


ISSN/ISBN: 0149-2918
PMID: 7448844
Document Number: 163703
Samples of sputum were collected from ten patients with chronic respiratory diseases following treatment with Varidase (streptodornase and streptokinase) buccal tablets, four tablets per day for a period of seven days, and were compared with specimens obtained before the therapy in terms of rheological and cytochemical parameters. The study revealed a tendency for the respiratory secretion to show a lowered yield point and a decrease in mucous fibers after the therapy, thus suggesting, to some extent, the efficacy of the drug as an expectorant.

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