A micro-neutralization test for flavivirus antibodies

Ksiazek, T.G.; Liu, J.Y.

Southeast Asian Journal of Tropical Medicine and Public Health 11(2): 189-193

1980


ISSN/ISBN: 0125-1562
PMID: 6254186
Document Number: 163260
A micro-neutralization test for the detection of flavivirus antibodies is described. The test utilizes the PS line of cells in flat bottomed microtiter plates to detect the neutralization of cytopathic effect by specific antibodies. Cross-neutralization of flaviviruses found in Southeast Asia with homologous and heterologous hyperimmune mouse ascitic fluids revealed the test to be specific. The test is simple and inexpensive to perform.

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