Clinical observation of serous ferritin levels in obstetrics and gynecology--relation between maternal, fetal and neonatal sera
Kokuho, K.; Kurabayashi, M.; Okuyama, T.; Furuya, H.
Nihon Sanka Fujinka Gakkai Zasshi 32(11): 1775-1782
1980
ISSN/ISBN: 0300-9165 PMID: 7240832 Document Number: 161218
By the 2-site radioimmunoassay, maternal, umbilical and neonatal human sera were studied. Non-heme Fe contents of some organs of maternal, fetal and neonatal mice were analyzed and each segment measured. The serum ferritin levels of early, mid- and late pregnancy were 34.1 .+-. 19.0, 22.9 .+-. 12.2 and 19.4 .+-. 11.7 ng/ml, respectively, in the non-anemic group and 15.1 .+-. 7.8, 10.2 .+-. 6.7 and 5.2 .+-. 2.2 ng/ml in the anemic group, both decreasing in the course of the pregnancy. The serum ferritin levels of umbilical cords were significantly higher than those of the mothers and no relationship was found between them. According to the maternal serum ferritin levels, grouped into < 15 ng/ml, > 15 ng/ml and < 30 ng/ml and > 30 ng/ml, a significant difference in umbilical serum ferritin levels and was found between the 3 groups. Serum ferritin levels in the neonate increased to a peak on the 4th-5th day after birth, as did the serum bilirubin levels. Non-heme Fe contents of some organs of pregnant mice varied a great deal but the SII (containing the ferritin) segment increased during pregnancy and during the puerperium.