Experimental model of high-dosage immunological tolerance to Shigella sonnei lipopolysaccharide
Borisov, V.A.; Gofman, I.L.
Mikrobiolohichnyi Zhurnal 42(6): 723-726
1980
ISSN/ISBN: 0201-8462 PMID: 7007829 Document Number: 160421
A low-toxic preparation with a residual antigenicity is obtained by alkaline treatment of S. sonnei lipopolysaccharide. A high-dose administration of this preparation to mice induced in them a state of immune tolerance to the initial lipopolysaccharide form.
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