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Penicillin G procaine: a possible cause of embryonic death in swine

Nurmio, P.; Schulman, A.

Veterinary Record 106(5): 97-98

1980

ISSN/ISBN: 0042-4900
PMID: 7361408
Document Number: 159961
A field case involving seven recently inseminated Yorkshire sows injected with procaine penicillin is described. About four hours after injection, the pigs showed shivering, incoordination, vomiting, extreme lassitude, pyrexia (41 deg C) and total inappetence. In each case, a thick, white mucous discharge appeared from the vulva one to three days after injection, with distinct embryos in some cases. Further experiments on pregnant and fattening pigs indicated that untoward reactions to penicillin could arise in swine, particularly embryonic death. [There is criticism of the author's conclusions on pages 207-208 of the same journal.].

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