Assessment of haemodynamic changes and acid-base equilibrium during hypovolaemia and after infusion of plasma substitutes in dogs
Filczewski, M.; Oledzka, K.; Szymańska-Kosmala, M.; Bogucka, E.
Acta Physiologica Polonica 31(2): 201-208
1980
ISSN/ISBN: 0044-6033 PMID: 6156574 Document Number: 157329
The following hemodynamic values were determined in anesthetized mongrel dogs: heart rate, systolic blood pressure in the ascending aorta, left ventricular pressure at the peak dp/dt , left ventricular end-diastolic pressure, time interval from Q in ECG to the onset of the systolic wave of dp/dt, time interval from Q in ECG to peak dp/dt, maximum rate of left ventricular pressure rise, femoral arterial flow and certain indices of left ventricular contractility. Infusion of a modified gelatin solution, Fluigel, prevented hemodynamic and metabolic changes produced by experimental hypovolemia more effectively than infusion of Plasmagel.