Acid-base equilibrium of D-(--)-alpha-aminophenylacetic acid

Nys, P.S.; Abramova, E.E.; Kolygina, T.S.; Savitskaia, E.M.; Nys, P.S; Abramova, E.E; Kolygina, T.S; Savitskaia, E.M

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Acid-base equilibrium of D- (--) -alpha-aminophenylacetic acid

Nys, P.S.; Abramova, E.E.; Kolygina, T.S.; Savitskaia, E.M.

Antibiotiki 22(5): 405-408

1977

ISSN/ISBN: 0003-5637

PMID: 879724

Document Number: 110972

Potentiometric titration was performed and the ioniziation macroconstants of D-(--)-alpha-aminophenylacetic acid and its methyl ether were determined. The constants were used for estimation of 4 microconstants of D-(--)-alpha-aminophenylacetic acid and the constants of the tautomeric equilibrium of the zwitter-ionic and neutral forms of the amino acid. Minimum solubility of D-(--)-alpha-aminophenylacetic acid was determined and pH-dependence of its solubility was estimated.