Lymphoid cell ultrastructure in experimental tuberculous granuloma
Erokhin, V.V.; El'shanskaia, M.P.
Biulleten' Eksperimental'noi Biologii i Meditsiny 90(12): 738-742
1980
ISSN/ISBN: 0365-9615 PMID: 7470614 Document Number: 156066
There are two groups of activated cells differing both in ultrastructure and manifestations of functional activity in lymphoid populations participating in the formation of tuberculous granuloma. In group 1 lymphoid cells, the development of intracellular structure is associated with an intense synthetic and secretory activity. Group 2 cells are mainly characterized by absorption function realized by means of active pinocytosis. The heterogeneity of subcellular organization of lymphoid cells in experimental tuberculosis reflects differences in their functional specialization. Study of tuberculous granuloma lymphocytes by scanning electron microscopy does not allow the lymphocytes to be identified as T and B cells without immunologic marker reactions.