Giant cell reparative granuloma concurrent with squamous cell carcinoma of the temporal bone: a case report and review of the literature

Larbcharoensub, N.; Pongtippan, A.; Tuntiyatorn, L.; Cheewaruangroj, W.; Bhummichitra, K.; Sirikulchayanonta, V.

Journal of the Medical Association of Thailand 90(2): 369-375

2007


ISSN/ISBN: 0125-2208
PMID: 17375645
Document Number: 2712
A case of giant cell reparative granuloma concurrent with squamous cell carcinoma of the right temporal hone in a 44-year-old man with clinically presenting otorrhea from the mass of the right acoustic canal with hearing loss is reported The histopathological examination of the lesion characterizes by multinucleated giant cells with in a fibroblastic stroma and area of keratinizing squamous cell carcinoma. GCRG may have been a local reaction provoked by the squamous cell carcinoma. Clinical and pathological features with briefly reviewed relevant literatures of temporal GCRG,describing g, 24 cases are discussed The patients have the mean age of 34.8 years. The ages of the patients ranged from 4 months to 72 years old. Temporal hone GCRG shows a male predilection of approximately 3:1. The frequently presenting symptoms of temporal hone GCRG are hearing loss, mass, tinnitus, otalgia, otorrhea, vertigo, headache, facial weakness, and diplopia. This is the first reported description in the literature of temporal bone GCRG concurrent with squamous cell carcinoma.

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Giant cell reparative granuloma concurrent with squamous cell carcinoma of the temporal bone: a case report and review of the literature