Effect of cytostatics administration in rats on leukocyte cytochemical markers
Orzechowska-Juzwenko, K.
Archivum Immunologiae et Therapiae Experimentalis 28(5): 663-683
1980
ISSN/ISBN: 0004-069X PMID: 7194023 Document Number: 155462
The influence of cytostatic drugs (busulphan, chlorambucil, prednisone, 6-mercaptopurine, L-asparaginase) on the activity of alkaline and acid phosphatase, alpha-naphtolacetate esterase and the content of glycogen and lipids in leukocytes of peripheral blood in healthy rats was investigated. No analogy was reported between the changes of cytochemical reactions in healthy population of leukocytes in rats as compared with the changes (observed in preceding papers) of cytochemical reactions in leukocytes of patients with leukemia under the influence of the same cytostatic drugs.