Spontaneous liver tumors in aged germfree Wistar rats

Pollard, M.; Luckert, P.H.

Laboratory Animal Science 29(1): 74-77

1979


ISSN/ISBN: 0023-6764
PMID: 220465
Document Number: 153866
Liver tumors, ranging from benign nodules to carcinomas, developed spontaneously in 115 (87%) of 132 germfree Wistar rats beyond the age of 30 months. In addition, the rats developed a high incidence of benign adenomas of endocrine glands and of the breasts.

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