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Spontaneous tumors of the nervous system in albino rats

Fitzgerald, J.E.; Schardein, J.L.; Kurtz, S.M.

Journal of the National Cancer Institute 52(1): 265-273

1974

ISSN/ISBN: 0027-8874
PMID: 4810967
Document Number: 76118
A retrospective review of P.M. examinations of 7803 albino rats revealed 34 tumours originating in the brain or meninges for an overall incidence of 0.44%. In addition, 4 tumours of ganglion cell origin were found. The most frequent brain tumour was astrocytoma; others included oligodendroglioma, ependymoma, meningioma, ganglioneuroma, and optic nerve glioma. The tumours had a predeliction for male rats and occurred at an average age of 17-18 months.

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