Triaminotricarboxylic amino acid oxidation productions of actinoidin and ristomycin
Berdnikova, T.F.; Tokareva, N.L.; Potapova, N.P.; Lomakina, N.N.
Antibiotiki 24(4): 251-254
1979
ISSN/ISBN: 0003-5637 PMID: 87147 Document Number: 150960
Aromatic acids with three benzene nuclei bound through oxygen were obtained from actinoidin and ristomycin on their oxydation with permanganates of methylated aglycones and peptides. The structures of the methyl esters of these acids were determined by spectral methods. They are the following: methyl-3,5-bis-(4-methoxycarbonyl-phenoxy)-4-methoxybenzoate (from ristomycin) and methyl-3-(2-chlor-4-methoxycarbonyl-phenoxy)-5-(4-methoxycarbonyl-phenoxy)-4-methoxybenzoate (from actinoidin). The compounds are the aromatic parts of the molecules of the unusual triaminotricarboxylic amino acids present in the aglycones of all antibiotics of the group of polycyclic glycopeptides.