Is the sodium ionic channel a cyclic hexapeptide?
Lejeune, J.
Annales de Genetique 22(2): 108-111
1979
ISSN/ISBN: 0003-3995 PMID: 315200 Document Number: 148791
A cyclic hexapeptide affords a model of an ionic channel, permeable to Na+ but not to K+. The selective fixation of tetrodotoxin and saxitoxin could occur through six hydrogen bonds, one with each of carbonyles of the crown exposed at the outside of the membrane.
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