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Regulation of potassium channel function in T lymphocytes by intracellular second messengers for calcium, cyclic AMP and membrane lipid metabolites

Teisseyre, A.

Postepy Higieny i Medycyny Doswiadczalnej 54(3): 381-390

2000

ISSN/ISBN: 0032-5449
PMID: 10941272
Document Number: 522812
This review focuses on the influence of well-known intracellular second messengers on the activity of potassium channels expressed in human T lymphocytes. Basic biophysical properties of the channels are briefly presented. Available data on the regulatory role of intracellular calcium and cyclic AMP is reviewed. Finally, a possible influence of lipid compounds, especially high-density lipoproteins, lysophospholipids and sphingolipids, on the expression and activity of potassium channels in human T lymphocytes is discussed.

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