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Intracellular modulation of membrane channels by cyclic AMP-mediated protein phosphorylation in peptidergic neurons of Aplysia

Strumwasser, F.; Kaczmarek, L.K.; Jennings, K.R.

Federation Proceedings 41(13): 2933-2939

1982

ISSN/ISBN: 0014-9446
PMID: 6292000
Document Number: 196393
The peptidergic bag cell neurons of the opisthobranch mollusc Aplysia control egg laying and its correlated behavior by release of the neuroactive peptide, egg-laying hormone, during the extended electrical discharge termed afterdischarge. This paper examines the evidence for the involvement of cyclic AMP (cAMP) and protein phosphorylation in the mediation of this electrical afterdischarge. It is concluded that an important component in the mechanism of afterdischarge is the suppression of a potassium channel, mediated by cAMP-dependent protein kinase-induced protein phosphorylation. The exact identity of the potassium channel remains to be worked out.

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Azhar, S.; Menon, M.; Menon, K.M. 1980: Receptor mediated gonadotropin action in the ovary. Modulation of progesterone response in isolated rat ovarian cells by gonadotrophin, cholera enterotoxin and cyclic nucleotides: requirement for RNA and protein synthesis Acta Endocrinologica 95(4): 528-539
Wei, Y.; Zhang, C.; Miao, X.; Xing, F.; Liu, X.; Zhao, H.; Zhan, X.; Han, D. 2009: Effects of glucocorticoid on cyclic nucleotide-gated channels of olfactory receptor neurons Journal of Otolaryngology - Head and Neck Surgery 38(1): 90-95
Cornwell, T.L.; Pryzwansky, K.B.; Wyatt, T.A.; Lincoln, T.M. 1991: Regulation of sarcoplasmic reticulum protein phosphorylation by localized cyclic GMP-dependent protein kinase in vascular smooth muscle cells Molecular Pharmacology 40(6): 923-931
Liu, J.; Bangalore, R.; Rutledge, A.; Triggle, D.J. 1994: Modulation of L-type Ca2+ channels in clonal rat pituitary cells by membrane depolarization Molecular Pharmacology 45(6): 1198-1206
Bloch, B.; Lenys, D.; Gouget, A.; Fellmann, D.; Bugnon, C. 1979: Immunocytologic analysis, in rat hypothalamus, of neurons producing peptides related to endorphin, ACTH, MSH and beta-LPH. Comparison with other peptidergic and monoaminergic neurons Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 173(4): 719-724
Rao, T.S.; Cler, J.A.; Emmett, M.R.; Mick, S.; Iyengar, S.; Wood, P.L. 1990: BMY-14802 antagonizes harmaline- and D-serine-induced increases in mouse cerebellar cyclic GMP: neurochemical evidence for a sigma receptor-mediated functional modulation of responses mediated by the N-methyl-D-aspartate receptor complex in vivo Molecular Pharmacology 37(6): 978-982
Zabłocki, K.; Makowska, A.; Duszyński, J. 2001: Mitochondrial uncoupling does not influence the stability of the intracellular signal activating plasma membrane calcium channels Acta Biochimica Polonica 48(1): 157-161
Nairn, A.C.; Greengard, P. 1983: Cyclic GMP-dependent protein phosphorylation in mammalian brain Federation Proceedings 42(14): 3107-3113
Postnov, I.V.; Kravtsov, G.M.; Kotelevtsev, I.V.; Dulin, N.O.; Postnov, I.Iu. 1987: Changes in erythrocyte volume in relation to characteristics of protein phosphorylation of the membrane cytoskeleton in hypertension: role of protein kinase C Kardiologiia 27(8): 60-65
Chida, K.; Hashiba, H.; Sasaki, K.; Kuroki, T. 1986: Activation of protein kinase C and specific phosphorylation of a Mr 90,000 membrane protein of promotable BALB/3T3 and C3H/10T1/2 cells by tumor promoters Cancer Research 46(3): 1055-1062
Kadokami, T.; Shimokawa, H.; Fukumoto, Y.; Ito, A.; Takayanagi, T.; Egashira, K.; Takeshita, A. 1996: Coronary artery spasm does not depend on the intracellular calcium store but is substantially mediated by the protein kinase C-mediated pathway in a swine model with interleukin-1 beta in vivo Circulation 94(2): 190-196
Kimball, S.R.; Jefferson, L.S. 1992: Regulation of protein synthesis by modulation of intracellular calcium in rat liver American Journal of Physiology 263(5 Pt 1): E958-E964
Teisseyre, A. 2000: Regulation of potassium channel function in T lymphocytes by intracellular second messengers for calcium, cyclic AMP and membrane lipid metabolites Postepy Higieny i Medycyny Doswiadczalnej 54(3): 381-390
Stepanova, I.V.; Kostiuk, P.H.; Kostiuk, O.P. 2005: Dynamic interaction between plasma membrane structures and intracellular calcium stores in neurons of the spinal cord ganglia Fiziolohichnyi Zhurnal 51(1): 19-25
Yang, X.; Diehl, A.M.; Wand, G.S. 1996: Ethanol exposure alters the phosphorylation of cyclic AMP responsive element binding protein and cyclic AMP responsive element binding activity in rat cerebellum Journal of Pharmacology and Experimental Therapeutics 278(1): 338-346
Vicini, S.; Mienville, J.M.; Costa, E. 1987: Actions of benzodiazepine and beta-carboline derivatives on gamma-aminobutyric acid-activated Cl- channels recorded from membrane patches of neonatal rat cortical neurons in culture Journal of Pharmacology and Experimental Therapeutics 243(3): 1195-1201
Delgado-Escueta, A.V.; Horan, M. 1983: Effects of seizures on ion transport and membrane protein phosphorylation Advances in Neurology 34: 311-323
Sorenson, E.M.; Gallagher, J.P. 1996: The membrane hyperpolarization of rat dorsolateral septal nucleus neurons is mediated by a novel nicotinic receptor Journal of Pharmacology and Experimental Therapeutics 277(3): 1733-1743
Chatila, T.A.; Geha, R.S. 1988: Phosphorylation of T cell membrane proteins by activators of protein kinase C Journal of Immunology 140(12): 4308-4314
Solntseva, E.I.; Borisova, O.V.; Skrebitskiĭ, V.G. 1995: Induction of a delayed cyclic AMP-sensitive sodium current in mollusk neurons by G-protein activators Biofizika 40(1): 110-114