In vitro effects of single alkylating agents on normal peripheral blood lymphocytes
Brody, J.I.
Journal of Laboratory and Clinical Medicine 94(1): 114-122
1979
ISSN/ISBN: 0022-2143 PMID: 469367 Document Number: 146320
The separate in vitro effects of HN2 rendered the in vitro HN2 innocuous but L-PAM remained cytotoxic. Stimultaneous lectin-induced blastogenesis proceeded unaltered. Finally, comparisons between 72 and 4 h drug exposures imply that interference with intracellular synthesis occurs promptly, continues after drug removal and is related quantitatively to drug concentration rather than to duration of contact.
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