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Effect of mouse genotype on the hematopoietic stem cell count. II. the number of hematopietic stem cells in BALB/c and CC57BR strain mice differing by the level of endogenous colony formation

Kozlov, V.A.

Genetika 15(10): 1793-1797

1979

ISSN/ISBN: 0016-6758
PMID: 499802
Document Number: 145817
The number of stem hematopoietic cells in the hematopoietic organs of mice of BALB/c and CC57BR strains and (CC57BRXBALB/c)F1 hybrids was studied by the method of exogenous colony-forming units. The assay of migration of stem cells from the bone marrow to the spleen was carried out. It was found that the spleen and the bone marrow of mice of the studied genotypes contain approximately the same relative number of hematopoietic stem cells. The number of stem cells which migrate from the bone marrow to the spleen is greater in the mice of BALB/c strain than in the CC57BR mice.

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