4-nitro-4' isothiocyane-diphenylamine--a new anthelmintic in hookworm infestation
Gupta, P.S.; Gambhir, D.S.; Oswal, S.; Kumar, N.
Journal of Tropical Medicine and Hygiene 82(6): 117-119
1979
ISSN/ISBN: 0022-5304 PMID: 501765 Document Number: 143649
4-Nitro-4'-isothiocyane diphenylamine (Go9333) was evaluated on 61 patients infected with Necator americanus and 39 with Ancylostoma duodenale. 7 different treatment regimes were assessed on the basis of percentage reduction of eggs in the faeces at 14 days after treatment. The best dosage schedule appeared to be 30 mg/kg body weight in a single dose, which was effective against both species (100% reduction in egg counts in all of 20 patients).
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