Decomposition of human blood cholesterol by the enzyme from Actinomyces lavendulae
Imshenetskiĭ, A.A.; Nikitin, L.E.; Nazarova, T.S.; Shirshova, G.A.; Muntian, L.N.
Prikladnaia Biokhimiia i Mikrobiologiia 15(5): 715-718
1979
ISSN/ISBN: 0555-1099 PMID: 514995 Document Number: 143161
In vitro experiments with enzymic decomposition of cholesterol contained in the human blood were carried out. The enzyme was obtained from the mycelium of Actinomyces lavendulae. As a result of incubation of blood samples in the presence of the enzyme at 37 degrees, the cholesterol content decreased and reached 30--43% of the initial value within 2 hours. The enzyme showed its specific effect only upon free cholesterol but not on its esters.