Alphalipoprotein cholesterol and arterial cholesterol in human uterine arteries

Bondjers, G.; Wiklund, O.; Olofsson, S.O.

Artery 8(4): 388-392

1980


ISSN/ISBN: 0098-6127
PMID: 7213045
Document Number: 167903
It has been suggested that HDL may protect against clinical complications to atherosclerosis by stimulating cholesterol elimination from arterial tissue. To test this hypothesis alphalipoprotein cholesterol was related to arterial cholesterol in a group of women undergoing hysterectomy due to uterus myoma. A significant, inverse correlation between alphalipoprotein cholesterol and the cholesterol: DNA ratio in arterial tissue with intact endothelium was observed. This supports the hypothesis that HDL may participate in cholesterol removal from arterial tissue. Available data seem to favour the possibility that cholesterol is primarily effective in the elimination of cholesterol from the extracellular compartment.

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