Single daily dose carbimazole in the treatment of Grave's disease
Yap, P.K.
Singapore Medical Journal 20(4): 447-450
1979
ISSN/ISBN: 0037-5675 PMID: 583526 Document Number: 142804
The effectiveness of a single daily dose of carbimazole in the treatment of Grave's disease was well documented but has not received wide clinical usage. Twenty-four patients with Grave's disease (9 of which had already been on treatment with the conventional thrice daily regime for an average duration of 3 mo.) were given a single daily dose of carbimazole to induce and maintain a remission. Only one patient failed to achieve a satisfactory remission. Once in remission, a single daily dose of carbimazole was effective in maintaining it. A distinct patient preference for the single daily dose regime was noted.