Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria
Ndiaye, J.Louis.A.; Faye, B.; Diouf, A.M.; Kuété, T.; Cisse, M.; Seck, P.A.; Brasseur, P.; Same-Ekobo, A.; Lameyre, V.; Gaye, O.
Malaria Journal 7: 16
2008
ISSN/ISBN: 1475-2875 PMID: 18205945 DOI: 10.1186/1475-2875-7-16Document Number: 200515
We present a case of an individual who presented with acute severe mitral regurgitation in the setting of an inferior ST elevation myocardial infarction. Both transthoracic and transesophageal echocardiography demonstrated a posteriorly directed eccentric jet of severe mitral regurgitation with flail anterior mitral valve leaflet attached presumably to the anterior papillary muscle. Intraoperative findings demonstrated rupture of the postero-medial papillary muscle attached via chords to the anterior mitral valve leaflet. This case serves to remind us that both the anterior and posterior leaflets of the mitral valve are attached to both papillary muscle heads. The direction and eccentricity of the mitral regurgitant jet on echocardiography helps to locate the leaflet involved, but not necessarily the coexisting papillary muscle pathology.