The role of nicergoline in the symptomatic treatment of arterial hypertension and chronic cerebrovascular insufficiency. a study on 359 observations
Dauverchain, J.
Arzneimittel-Forschung 29(8a): 1308-1310
1979
ISSN/ISBN: 0004-4172 PMID: 395956 Document Number: 142506
An examination was carried out on the efficacy of 10-methoxy-1,6-diemethyl-ergoline-8 beta-methanol-(5-bromonicotinate) (nicergoline, Sermion) on the symptoms of functional side effects of arterial hypertension and chronic circulatory insufficiency as regards the psychomotoric activity and the relational activity; 359 patients suffering from crebrovascular insufficiency were included in the study. The compound was applied in a daily dose of 10 mg i. m. for 5 days and then in a daily dose of 15 mg orally for 1 month. In the entire symptom complex of cerebro-vascular insufficiency a positive effect of nicergoline could be observed; the results of all clinical criteria and their therapeutic relevance are discussed.