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Effect of lithium oxybutyrate on excitability of the cortex and some subcortical structures in rabbit brain

Saratikov, A.S.; Alekseeva, L.P.; Agarkova, V.P.; Zamoshchina, T.A.

Biulleten' Eksperimental'noi Biologii i Meditsiny 88(11): 574-576

1979

ISSN/ISBN: 0365-9615
PMID: 540150
Document Number: 142399
Lithium oxybutyrate microinjections (10 mg/ml) produce a depressant action on spontaneous bioelectrical activity of the cortex and subcortical structure. The drug brings down excitability of the motor cortex, hippocampus, caudate nucleus, thalamus, posterior hypothalamus and mesencephalic reticular formation; it also raises excitability of the tonsils. The depressant effect of lithium oxybutyrate is superior to that of lithium chloride.

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