Study of the electrophoretic and kinetic properties of erythrocyte glucose-6-phosphate dehydrogenase in hereditary enzyme deficiencies. Description of a new variant of glucose-6-phosphate dehydrogenase: the Gd Kremenchug
Tokarev, Y.N.; Chernyak, N.B.; Batishchev, A.I.; Lamzina, N.V.; Alexeyev, G.A.
Nouvelle Revue Francaise d'Hematologie 20(4): 557-564
1979
ISSN/ISBN: 0029-4810 PMID: 440960 Document Number: 140593
A study of the activity of human erythrocyte G-6-PD has been completed on a great number of normal controls, coming from different regions of the USSR. This study has led to the discovery of a new variant of erythrocytic Gd, which was named "Kremenchug" from the origin of the patient. This new Gd, has a very low Km for G-6-P, and has a greater affinity for 2-deoxyglucose-6-phosphate. The maximal activity versus the pH of the medium is also characteristic of this new Gd.