Experimental comparative study of acute toxicity and gastric tolerance of eterylate, benorylate and acetylsalicylic acid
Alonso, S.; Armijo, M.; Piña, M.
Archivos de Farmacologia y Toxicologia 4(3): 349-356
1978
ISSN/ISBN: 0304-8616 PMID: 34365 Document Number: 137355
Eterylate is 2.0-2.5 times less toxic than benorylate and acetylsalicylic acid, respectively, by oral acute toxicity studies in mice. Gastrointestinal lesions induced by these 3 compounds during 4 and 24 wk could be classified as follows: eterylate < benorylate < acetylsalicyclic acid. Studies of ulcer production and fecal blood loss apparently also show that eterylate is better tolerated than benorylate and acetylsalicylic acid.
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