Shikimic acid and quinic acid are not mutagenic in the Ames assay
Jacobsen, L.B.; Richardson, C.L.; Floss, H.G.
Lloydia 41(5): 450-452
1978
ISSN/ISBN: 0024-5461 PMID: 362106 Document Number: 136951
Shikimic acid, reported to cause tumors in mice, and its close structural analog, quinic acid, both ubiquitous constituents of higher plants, were found not to be mutagenic in the Ames Salmonella typhimurium assay when tested with and without the rat liver microsomal activation system.
Document emailed within 1 workday
Related Documents
Korth, H. 1973: Formation of gallic acid from quinic acid by Enterobacter cloacae and Pseudomonas fluorescens Archiv für Mikrobiologie 89(1): 67-72Loknitskaia, N.N.; Rotenberg, I.S.; Fonshteĭn, L.M.; Shuliakovskaia, T.S. 1986: Study of promutagen biotransformation in the Ames test. III. the role of conjugation with glucuronic acid and sulfate in the modification of mutagenic effect of nitrosomorpholine, diethylnitrosamine and cyclophosphamide Genetika 22(9): 2259-2264
Seifter, E.; Rettura, G.; Reissman, D.; Kambosos, D.; Levenson, S.M. 1971: Nutritional response to feeding L-phenyllactic, shikimic and D-quinic acids in weanling rats Journal of Nutrition 101(6): 747-754
Sun, K.L.; Li, R.S.; Lei, X.H. 1990: Studies on the synthesis and bioactivity of some new shikimic acid derivatives Yao Xue Xue Bao 25(1): 73-76
Kodama, K.; Yamanaka, K.; Nakata, T.; Aoyama, M. 1986: Liquid-chromatographic assay of urinary vanillylmandelic acid and homovanillic acid, with clean-up by on-column injection of acetonitrile or methanol Clinical Chemistry 32(10): 1944-1947
Baumann, L.S.; Oresajo, C.; Yatskayer, M.; Dahl, A.; Figueras, K. 2013: Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris Journal of Drugs in Dermatology: Jdd 12(3): 266-269
Strizhel'chik, N.G.; Kul'shin, V.E. 1994: The mutagenic and modifying properties of new gelatinous substances studied by using the Ames test Tsitologiia i Genetika 28(3): 91
Bhatia, K.G.; Phatak, M.K.; Chitnis, M.P.; Shetty, P.A.; Jussawalla, D.J. 1979: Microbiological assay for antifolate using folic acid assay method Indian Journal of Cancer 16(2): 35-36
Mogi, M.; Motohashi, M.; Hirota, T.; Ohshima, K.; Takahashi, N.; Kinoshita, Y.; Tanigawa, M.; Yoshinobu, T.; Koya, Y.; Masutani, M. 1990: Basic study on the chemosensitivity test by miniaturized improved nucleic acid precursor incorporation assay (MINi assay) Gan to Kagaku Ryoho. Cancer and ChemoTherapy 17(1): 89-95
Shapiro, A.A.; Meksin, V.A.; Abilev, S.K.; Akin'shina, L.P.; Fonshteĭn, L.M. 1978: Mutagenic activity of antitubercular preparations: isonicotinic acid hydrazide and its derivatives Tsitologiia i Genetika 12(4): 343-348
Ohtani, S.; Yamamoto, K. 1991: Age estimation by amino acid racemization in teeth--a comparison of aspartic acid with glutamic acid and alanine as indicators Nihon Hoigaku Zasshi 45(2): 119-123
Anton, A.H.; Berk, A.I. 1990: Electrochemical, fluorometric, and spectrophotometric analysis for 5-hydroxyindoleacetic acid, homovanillic acid, and vanillylmandelic acid in urine Clinical Chemistry 36(11): 1990
Manku, M.S.; Morse-Fisher, N.; Horrobin, D.F. 1988: Changes in human plasma essential fatty acid levels as a result of administration of linoleic acid and gamma-linolenic acid European Journal of Clinical Nutrition 42(1): 55-60
Murty, C.N.; Verney, E.; Sidransky, H. 1976: Effect of tryptophan on polyriboadenylic acid and polyadenylic acid-messenger ribonucleic acid in rat liver Laboratory Investigation; a Journal of Technical Methods and Pathology 34(1): 77-85
Sawada, K.; Kawaura, A.; Tanida, N.; Shimoyama, T. 1986: Short-term observation on the behavior of intrarectally instilled chenodeoxycholic acid, lithocholic acid and 5 beta-chol-3-en-24-oic acid in rats Tokushima Journal of Experimental Medicine 33(3-4): 29-37
Tsou, M.F.; Hung, C.F.; Lu, H.F.; Wu, L.T.; Chang, S.H.; Chang, H.L.; Chen, G.W.; Chung, J.G. 2000: Effects of caffeic acid, chlorogenic acid and ferulic acid on growth and arylamine N-acetyltransferase activity in Shigella sonnei (group D) Microbios 101(398): 37-46
Xu, X.-k.; Chen, Z.-y.; Liao, L.-p.; Zhang, Z.-j.; Wang, Z.-t. 2015: Determination of scopolin, chlorogenic acid, scopoletin, isochlorogenic acid A, isochlorogenic acid B and isochlorogenic acid C in plants of Erycibe Zhongguo Zhong Yao Za Zhi 40(6): 1119-1122
Lee, C.; Boos, M. 1987: Automated turbidimetric assay of serum haptoglobin by the Ames "Optimate" Clinical Chemistry 33(8): 1466
Kinoshita, Y.; Yamada, S.; Haraguchi, K.; Takayanagi, T.; Mori, Y.; Takahashi, T.; Haruki, E. 1988: Determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid in dried urine on filter-paper discs by high-performance liquid chromatography with coulometric electrochemical detection for neuroblastoma screening Clinical Chemistry 34(11): 2228-2230
Li, Y.; Guo, Z.-T.; Gong, X.-C.; Qu, H.-B. 2013: Simultaneous determination of danshensu, hydroxysafflor yellow A, rosmarinic acid, lithospermic acid, salvianolic acid B in water extract of mixed salviae miltiorrhizae radix et rhizoma and carthami flos by HPLC Zhongguo Zhong Yao Za Zhi 38(11): 1653-1656