Vascular reactivity and catecholamine excretion in hypertension
Podkolodnaia, O.A.; Shterental', I.S.; Dzizinskiĭ, A.A.; Genina, V.A.
Kardiologiia 18(11): 42-45
1978
ISSN/ISBN: 0022-9040 PMID: 723141 Document Number: 131188
Increased vascular reactivity to noradrenaline was revealed in patients with Stages I and II hypertensive disease; the reaction to the sympathomimetic agent of indirect action ephedrine remained at the control level. A salt load increased the discrepancy between the level of the reactions to these two agents. It is suggested that processes of catecholamine storage and excretion in the tissues are disturbed in hypertensive disease and that sodium ions probably take part in this process. The daily excretion of noradrenaline was in negative relation with the reactivity to noradrenaline and correlated positively with the reactivity to angiotensin.