Determination of antimicrobial activity of a combination of acidamfenicol, clotrimazole and dexamethasone in vitro
Poitschek, C.; Thurner, J.; Haller, I.
Arzneimittel-Forschung 28(2): 232-234
1978
ISSN/ISBN: 0004-4172 PMID: 580383 Document Number: 130791
The in vitro antimicrobial activity of the antieczematic Bay f 4797 was studied. This combination drug contains the three active components acidamfenicol, clotrimazole and dexamethasone (prospective trade name: Baycuten). Various bacterial and fungal species of importance in dermatology served as test organisms. All the bacterial strains examined were found to be moderately susceptible to acidamfenicol; clotrimazole showed good inhibitory values agaisnt all the fungal species and the gram-positive bacterial strains. Additionally it was checked whether a synergistic or antagonistic interaction occurs with respect to the antimicrobial activity. An interference which could lead to impairment of the therapeutic activity was not observed.