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Rhythm of the daily fluctuations in lipid metabolic and fibrinolysis system indices in ischemic heart disease

Seliverstova, G.P.; Oranskiĭ, I.E.

Kardiologiia 18(2): 130-132

1978

ISSN/ISBN: 0022-9040
PMID: 633716
Document Number: 130453
The study was conducted on 22 patients with ischemic heart disease (I stage atherosclerosis according to the classification suggested by A. L. Myasnikov). Phase 24-hour fluctuations of the indices of lipid metabolism, blood coagulation, and fibrinolysis were revealed clearly. It was established that in the initial stage of the disease the diurnal rhythm of lipid metabolism does not differ from that in healthy persons. The rhythm of diurnal fluctuations in the function of the hemostasis system was marked by an increase in blood coagulation and decrease in the activity of fibrinolysis early in the morning, which created the conditions for intravascular thrombus formation.

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