Morphologic changes of the renal arteries following instrumental compression
Weigner, K.; Lymberopoulos, S.; Breining, H.
Der Urologe. Ausg. a 17(6): 395-398
1978
ISSN/ISBN: 0340-2592 PMID: 726166 Document Number: 125270
In the present work, light-microscopic changes in the renal arteries of the rabbit following instrumental compression for specific intervals are described: 1. Compression led to necrosis of whole layers of the vascular walls, which could already be observed under the light microscope after 3 h.--2. The degree of wall necrosis depends only on the pressure of the clamp: not on the duration.--3. Experience shows that, independent of the type of clamp, there is complete regeneration of the adventitia and media by the fourth postoperative week.--4. In all vessels, the residual effect is a 2--5 layer proliferation of the intima that extends over the entire clamped area for 4--8 weeks postoperatively.--5. In 2 out of 80 renal arteries, arterial thromboses developed.