Differential morphologic criteria in sarcomatous-like renal carcinoma
Piscioli, F.; Micoli, G.; Olivetti, G.
Tumori 62(2): 227-232
1976
ISSN/ISBN: 0300-8916 PMID: 1006812 Document Number: 108691
A human case of Grawitz tumor with a diffuse sarcomatous-like pattern is reported. This feature is regarded as the anaplastic evolution of a carcinoma, lacking glycogen and rich in lipids. Since this histochemical specificity is maintained in the sarcomatous-like fields, the search for lipids and serial sectioning examination of the neoplasm is mandatory unless ultrastructural analysis is available. This histological approach is useful when a pathologist, dealing with a lesion suggestive of soft tissue tumor, has to diagnose or exclude an epithelial origin for the neoplasm. Malignancy of the sarcomatous-like areas is shown by malignant nuclear B and BC structures that exclude the possibility of stromal desmoplasia.