Dysplasia of the renal artery. Morphologic and morphometric study of 16 cases
Gamallo Amat, C.; Palacios Calvo, J.; Madero, R.; Galeano Díaz, F.; Martínez-Piñeiro, J.A.; Contreras Rubio, F.
Archivos Espanoles de Urologia 39(3): 161-184
1986
ISSN/ISBN: 0004-0614 PMID: 3729558 Document Number: 275057
The term arterial dysplasia is applied to a group of lesions of different morphological evolutive characteristics; their common trait is being non-arteriosclerotic fibrous and fibromuscular proliferations of unknown origin. This paper analyzes the pathoanatomy and morphometry in 16 cases of renal artery dysplasia, and the results are compared with those of a control group of normal renal arteries obtained thorough autopsies. Intimal fibroplasis (1 case) shows morphological lesions that are undistinguishable from intimal changes secondary to other processes. Due to this fact, diagnosis can only be made after these processes have been excluded, in arteries showing normal morphometric parameters. Medial fibroplasia (7 cases) is more frequent in the third and fourth decades of life. It is characterized by deep disorganization of the medial layer, involving long extensions of the artery. Large-sized aneruysms area a frequent association. Perimedial fibroplasia (5 cases) shows fibromuscular proliferation outside the external elastic membrane. This lesion usually develops during the early stages of life hindering normal growth of the affected artery. Following morphometric studies, medial hyperplasia (3 cases) is considered as segmentary arterial hypoplasia, not associated to morphologic changes of the media. All these lesions are associated to intimal fibrosis, an added feature which conditions the evolution of arterial stenosis.