Eliminating Heterophilic Antibody Interference for Ferritin Detection Using Olympus F (ab') 2 Based Reagent

Grouzmann, E.; Dayer, N.; Bain, C.; Neville, C.M.; Mc, M.D.Cusker; Wang, R.Y.

Clinical Laboratory 54(9-10): 355-357

2008


ISSN/ISBN: 1433-6510
PMID: 19097493
Document Number: 12388
Interferences with the Olympus® immunoturbidimetric assay for ferritin have been reported because the antibodies used in the immunoassay are derived from rabbits. Rabbits are familiar pets known to be a risk factor for developing heterophilic (or interfering) antibodies. This report shows how the current Olympus Ferritin assay has been improved to eliminate the interference from heterophilic antibodies.

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Eliminating Heterophilic Antibody Interference for Ferritin Detection Using Olympus F(ab') 2 Based Reagent