Effect of certain sulphydryl compounds and dimethyl sulphoxide on potassium release by certain amines and proteins from Pseudomonas aeruginosa
Bernheim, F.
Microbios 19(77-78): 151-156
1977
ISSN/ISBN: 0026-2633 PMID: 101739 Document Number: 122775
Dithiothreitol, cysteine, and mercapto-ethanol inhibit K+ release from cells of Pseudomonas aeruginosa by amines and NH4Cl incubated at pH 8.5. The inhibitions are competitive for the monamines and NH4Cl but non-competitive for the diamines and spermidine. The percent inhibition is largest for tryptamine, least for spermidine and ethylene diamine. DMSO inhibits K+ release by monamines and certain proteins but not significantly by diamines and histamine. The inhibitions are competitive.