Effect of various technics in the determination of sensitivity of Pseudomonas aeruginosa to imipenem
Maugein, J.; Fourche, J.; Pellegrin, J.L.; Mormède, M.
Pathologie-Biologie 38(5): 362-365
1990
ISSN/ISBN: 0369-8114 PMID: 2114605 Document Number: 360561
The in vitro activity of imipenem was determined against 115 isolates of Pseudomonas aeruginosa. The susceptibility was compared according to two technics: disk diffusion method and minimal inhibitory concentration determinations (MIC), this, with three different Mueller Hinton agar (Diagnostics Pasteur, bioMérieux, Amor Equipement Scientifique) and two inocula. There is not inoculum effect. On the contrary, except for extreme values, there is discrepancies in the activity according to the medium. The correlation between zone diameters and MIC values is less good when Mérieux and AES Mueller Hinton agar were used.