Functional aspects of blood platelets in irradiated burros

Schneider, M.D.

American Journal of Veterinary Research 38(2): 209-216

1977


ISSN/ISBN: 0002-9645
PMID: 842918
Document Number: 118815
An extractable collagen-like stimulator of blood platelet aggregation was discovered in the aorta of a donkey which had survived for more than 24 years after exposure to a total-body dose of 545 R of gamma-radiation. The platelet-aggregating ability of this stimulator was nearly four times higher than that from the aorta of a control given to irradiation treatment. This could be a delayed radiation effect which could lead to the clinical syndrome characterized by depletion of megakaryocytes and platelets which has been observed in irradiated donkeys.

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