Interaction of Sindbis virus with a culture of cells producing oncornavirus
Gushchin, B.V.; Berezina, L.K.; Gushchina, E.A.; L'vov, D.K.; Klimenko, S.M.
Voprosy Virusologii 3: 326-331
1977
ISSN/ISBN: 0507-4088 PMID: 198967 Document Number: 118602
Electron microscopy and biophysical methods were used for examinations of primarily trypsinized chick fibroblast cell culture spontaneously producing C-type oncornavirus at 1, 6, and 24 hours after inoculation with Sindbis virus. During the first 6 hours rapid maturation and release of oncornavirus from cells were observed. At later intervals oncornavirus production was inhibited. It is assumed that in the system under study, biosynthesis of oncornavirus and Sindbis virus occur separately.