Apolipoprotein abnormalities in low and very low density lipoproteins in a type V hyperlipemia
Beucler, I.; Salmon, S.; Ayrault, M.; Raymond, J.P.; Etienne, J.; Polonovski, J.
Pathologie-Biologie 25(2): 95-99
1977
ISSN/ISBN: 0369-8114 PMID: 191781 Document Number: 118501
Abnormalities in VLDL and LDL apolipoproteins have been observed in the serum of an 11 year old girl with a type V hyperlipoproteinemia (VLDL + chylomicrons). This was shown with polyacrylamide gel electrophoresis and also with two dimensional immunoelectrophoresis. The LDL contain peptides which are not found in normal apo LDL. In the VLDL, heterogeneity of the lipopeptides is more marked that in normal VLDL, and there is an abnormal distribution of the apolipoproteins C or D.