Modified Giemsa technique for the study of characteristic chromosomes of leukemic C57Bl mice
Léonard, A.; Decat, G.; Maisin, J.R.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 171(3): 682-685
1977
ISSN/ISBN: 0037-9026 PMID: 71940 Document Number: 116490
G-banded karyotypes have been studied in C57Bl control mice and in animals developing leukemia after i.p. injection of acellular extract of spleen or lymph nodes from isologous animals showing radiation induced leukemia. No visible differences could be detected with respect to the number, size and position of the G-bands between the two groups of animals. From the present observations and from previous work with conventional staining methods, it can be concluded that the development of such leukemia does not involve the presence of chromosome abnormalities.