Sesquiterpene lactones. Part XV. new cytostatic active sesquiterpene lactone from herb of Anthemis nobilis L
Grabarczyk, H.; Drozdz, B.; Hladoń, B.; Wojciechowska, J.
Polish Journal of Pharmacology and Pharmacy 29(4): 419-423
1977
ISSN/ISBN: 0301-0244 PMID: 905207 Document Number: 112493
From fresh and dried herb (without inflorescences) of Anthemis nobilis L. a new sesquiterpene lactone C20H26O6 was isolated. This compound showed a cytotoxic activity at a level of ED50 HeLa -- 0-56 microgram/ml (1-5 x 10(-6) M), and ED50 KB -- 1.23 microgram/ml (3-5 x 10(-6) M), what qualifies it for further in vivo studies.