In vivo acylation of triglycerides and phosphoglycerides of liver subcellular fractions with palmitate-1-14C in rats fed vitamin A
Ram, G.C.; Misra, U.K.
International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 46(2): 180-186
1976
ISSN/ISBN: 0300-9831 PMID: 1032630 Document Number: 108661
Male Wistar rats weighing 90 to 100 g on a stock diet to appetite were given for 2 days 100 000 IU retinol and then killed. Controls were not given vitamin A. Palmitate-1-14C, 5 mu Ci/100 g bodyweight, was given intraperitoneally 20 min before the rats were killed. There was a significant rise in triglycerides in liver and in its mitochondrial, microsomal and supernatant fractions and also in total phospholipids and phosphatidyl choline in mitochondrial and microsomal fractions in rats given vitamin A. The incorporation of palmitate-1-14C into triglyceride of liver mitochondrial, microsomal and supernatant fractions of rats given vitamin A was significantly greater than in those of controls but there was no difference in incorporation into phosphatidyl ethanolamine and phosphatidyl choline.