Applications of bidimensional immunoelectrophoresis to hypersensitivity pneumonia by inhalation of organic antigens. its interest in relation to the classical immunodiffusion and immunoelectrophoresis methods
Aiache, J.M.; Jeanneret, A.; Molina, C.
Pathologie-Biologie 24(8): 525-529
1976
ISSN/ISBN: 0369-8114 PMID: 824606 Document Number: 107760
Bidimensional electrophoresis is of most interest for the diagnosis of extrinsic allergic alveolitis. In fact, this detecting method is more specific than classical immunoelectrophoresis. Thus patients showing with the classical methods precipitation lines with one or several antigens do not present everytime the corresponding clinical signs. These positive but false reactions cannot in any case appear with bidimensionnal electrophoresis. Generally, the patient showing at least two precipitation lines opposite one antigen in bidimensional electrophoresis always followed by an increase of IgG, does also present the clinical signs of the disease.