Study of the effect of tetracycline, prodigiosin and their combination on the dynamics of phagocytosis of plague bacteria
Popova, G.O.; Vinidchenko, N.N.; Mikhalevich, R.V.
Antibiotiki 21(5): 447-452
1976
ISSN/ISBN: 0003-5637 PMID: 1023817 Document Number: 106921
The advantage of the combined use of prodigiozan and tetracycline was observed in tissue culture of peritoneal macrophages of albino mice. Earlier digestion of the intracellular Y. pestis EV by the animal macrophages exposed to prodigiozan and treated with tetracycline was noted. It was shown that the macrophages preserved during several hours of cultivation in vitro their properties acquired in the animal organism under the effect of the substances administered.