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Protective effect of unithiol and its combination with magnesium sulfate in endotoxin poisoning and in infection by gram-negative bacteria

Grutman, M.I.; Persidskiĭ, I.V.; Frolov, V.M.; Nagornaia-Persidskaia, R.N.; Gushla, E.P.

Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 1: 23-26

1992

ISSN/ISBN: 0031-2991
PMID: 1625924
Document Number: 399299
It is shown that unithiol protects mice from death in intoxication by S. typhimurium and S. Sonnei lysates and in infection caused by S. typhimurium. Magnesium sulfate strengthens the protective effect of unithiol. It is suggested that the protective effect of unithiol is due to its antioxidant action.

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