Idiopathic inflammatory bowel disease in dogs and cats: 84 cases (1987-1990)
Jergens, A.E.; Moore, F.M.; Haynes, J.S.; Miles, K.G.
Journal of the American Veterinary Medical Association 201(10): 1603-1608
1992
ISSN/ISBN: 0003-1488 PMID: 1289345 Document Number: 399298
Idiopathic inflammatory bowel disease was diagnosed in 58 dogs and 26 cats, with signs of persistent gastroenteritis, failed responses to dietary trials, and histological evidence of cellular infiltrates unrelated to other causes of gastrointestinal tract inflammation. Clinical signs of large intestinal dysfunction, watery diarrhoea, vomiting and anorexia with weight loss were common. Nonspecific haematological, biochemical and radiographical abnormalities frequently were observed. Mucosal biopsy specimens, obtained endoscopically, were histologically evaluated for severity of mucosal epithelial damage. Mucosal erythema, friability, enhanced granularity, and ulceration or erosion were the predominant endoscopic lesions. Inflammatory bowel disease lesions of moderate severity predominated in the stomach, duodenum, and colon. Lymphocytic/plasmacytic infiltrates were limited to the lamina propria in biopsy specimens from all regions of the gastrointestinal tract.