The role of macrophages in the adjuvant effect on antibody production of Corynebacterium parvum
Watson, S.R.; Sljivić, V.S.
Clinical and Experimental Immunology 23(1): 149-153
1976
ISSN/ISBN: 0009-9104 PMID: 770033 Document Number: 105670
Spleen cells from mice pre-treated with C. parvum gave an enhanced in vitro antibody response to SRBC, but not to DNP-POL. This enhancing activity was associated with the adherent, but not the non-adherent spleen cell population and was found to be radioresistant. It is concluded that macrophages are directly involved in the adjuvant effect of C. parvum and the possible mechanisms of action are discussed.
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