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Effect of trasyslol on the permeability of the histo-hematic barrier in ischemic myocardium

Gatsura, V.V.; Prusachenko, V.K.

Biulleten' Eksperimental'noi Biologii i Meditsiny 81(6): 696-697

1976

ISSN/ISBN: 0365-9615
PMID: 1085179
Document Number: 105009
Ligation of the descending branch of the left coronary artery caused an increase in the permeability of the histo-hematic barrier of the myocardium for sulfacyl-sodium in the ischemic area and in the region adjacent to it. Trasylol proved to decrease the permeability of the histo-hematic barrier of the myocardium in the mentioned area, without influencing the intact zone. Fluoresceine test demonstrated the presence of membranotropic effect of trasylol; the preparation had no effect on the osmotic stability of erythrocytes in vitro.

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