Uptake of bovine serum albumin by rainbow trout from hypersmotic solutions: a model for vaccinating fish
Amend, D.F.; Fender, D.C.
Science 192(4241): 793-794
1976
ISSN/ISBN: 0036-8075 PMID: 1265480 Document Number: 104372
Immersion of juvenile rainbow trout (Salmo gairdneri) in a solution containing urea or NaCl at 1650 milliosmoles and 2% of bovine serum albumin (BSA) resulted in an uptake of BSA into the blood of the fish after a 3 min exposure. Similar blood levels of BSA were also obtained by placing the fish in 1650 milliosmoles of NaCl for about 2 min. and then immersing them in 2% BSA solution for 3 min. Uptake of BSA into the fish appeared to be primarily through the lateral line system and secondarily through the gills. The importance of these results to the possible immunization of fish is discussed.